Article
DNA methylation and copy number variation profiling of T-cell lymphoblastic leukemia and lymphoma.
Blood cancer journal - 28 Apr 2020
Haider Zahra, Landfors Mattias, Golovleva Irina, Erlanson Martin, Schmiegelow Kjeld, Flægstad Trond, Kanerva Jukka, Norén-Nyström Ulrika, Hultdin Magnus, Degerman Sofie
Abstract excerpt
Despite having common overlapping immunophenotypic and morphological features, T-cell lymphoblastic leukemia (T-ALL) and lymphoma (T-LBL) have distinct clinical manifestations, which may represent separate diseases. We investigated and compared the epigenetic and genetic landscape of adult and pediatric T-ALL (n = 77) and T-LBL (n = 15) patient samples by high-resolution genome-wide DNA methylation and Copy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
