Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial and socioeconomic contributions to premorbid functioning in psychosis: Impact on age at onset and treatment response.

European psychiatry : the journal of the Association of European Psychiatrists - 29 Apr 2020

Hatzimanolis Alex, Stefanatou Pentagiotissa, Kattoulas Emmanouil, Ralli Irene, Dimitrakopoulos Stefanos, Foteli Stefania, Kosteletos Ioannis, Mantonakis Leonidas, Selakovic Mirjana, Soldatos Rigas-Filippos, Vlachos Ilias, Xenaki Lida-Alkisti, Smyrnis Nikolaos, Stefanis Nicholas C

Abstract excerpt

BACKGROUND: Premorbid adjustment (PA) abnormalities in psychotic disorders are associated with an earlier age at onset (AAO) and unfavorable clinical outcomes, including treatment resistance. Prior family studies suggest that familial liability, likely reflecting increased genetic risk, and socioeconomic status (SES) contribute to premorbid maladjustment. However, their joint effect possibly indicating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Antipsychotic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Psychotic Disorders

Share to Risk Factors

Share to Schizophrenia

Share to Social Adjustment

Share to Socioeconomic Factors

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 32345391
DOI: 10.1192/j.eurpsy.2020.41
PMCID: PMC7355181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial and socioeconomic contributions to premorbid functioning in psychosis: Impact on age at onset and treatment response.PMID 32345391Read ↗

From premorbid adjustment dimensions to clinical outcomes: Exploring environmental stress and epigenetic influences on first-episode schizophrenia phenotypes.Semantic proximity Read ↗

Genetic liability, prenatal health, stress and family environment: risk factors in the Harvard Adolescent Family High Risk for schizophrenia study.Semantic proximity Read ↗

Polygenic risk scores mediating functioning outcomes through cognitive and clinical features in youth at family risk and controls.Semantic proximity Read ↗

Identifying extended psychosis phenotypes at school: Associations with socio-emotional adjustment, academic, and neurocognitive outcomes.Semantic proximity Read ↗

Psychopathology, personality traits and social development of young first-degree relatives of patients with schizophrenia.Semantic proximity Read ↗

Familial liability to schizophrenia and premorbid adjustment.Semantic proximity Read ↗

Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study.Semantic proximity Read ↗

Role of resilience in modifying the links between genetic propensity for mental disorders and irritability.Semantic proximity Read ↗

Polygenic risk for schizophrenia predicting social trajectories in a general population sample.Semantic proximity Read ↗

Exploring the effects of family and life events on genetic and environmental architecture of schizotypal and hypomanic dimensions: Insights from a twin studySemantic proximity Read ↗

Social risk or genetic liability for psychosis? A study of children born in Sweden and reared by adoptive parents.Semantic proximity Read ↗

Executive function mediates the effects of genetic liability to schizophrenia on behavior and functioning in a community sample of children and adolescents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.