Article
Genetic liability, prenatal health, stress and family environment: risk factors in the Harvard Adolescent Family High Risk for schizophrenia study.
Schizophrenia research - 1 Aug 2014
Walder Deborah J, Faraone Stephen V, Glatt Stephen J, Tsuang Ming T, Seidman Larry J
Abstract excerpt
OBJECTIVES: The familial ("genetic") high-risk (FHR) paradigm enables assessment of individuals at risk for schizophrenia based on a positive family history of schizophrenia in first-degree, biological relatives. This strategy presumes genetic transmission of abnormal traits given high heritability of the illness. It is plausible, however, that adverse environmental factors are also transmitted in these families....
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