Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene regulatory landscape of the sonic hedgehog locus in embryonic development.

Development, growth & differentiation - 1 Jun 2020

Amano Takanori

Abstract excerpt

The organs of vertebrate species display a wide variety of morphology. A remaining challenge in evolutionary developmental biology is to elucidate how vertebrate lineages acquire distinct morphological features. Developmental programs are driven by spatiotemporal regulation of gene expression controlled by hundreds of thousands of cis-regulatory elements. Changes in the regulatory elements caused by the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryonic Development
Share to Enhancer Elements, Genetic
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Hedgehog Proteins

Share to Phenotype

Source

Identifiers

PMID: 32343848
DOI: 10.1111/dgd.12668

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene regulatory landscape of the sonic hedgehog locus in embryonic development.PMID 32343848Read ↗

Comparative genomics of the Hedgehog loci in chordates and the origins of Shh regulatory novelties.Semantic proximity Read ↗

Mapping the temporal and functional landscape of Sonic Hedgehog signaling reveals new insights into early human forebrain developmentSemantic proximity Read ↗

Progressive Loss of Function in a Limb Enhancer during Snake Evolution.Semantic proximity Read ↗

Human developmental disorders and the Sonic hedgehog pathwaySemantic proximity Read ↗

The mechanisms of Hedgehog signalling and its roles in development and diseaseSemantic proximity Read ↗

Expanding the phenotypic expression of Sonic Hedgehog mutations beyond holoprosencephaly.Semantic proximity Read ↗

The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression.Semantic proximity Read ↗

The Sonic Hedgehog–Patched–Gli Pathway in Human Development and DiseaseSemantic proximity Read ↗

Sonic Hedgehog, a key development gene, experienced intensified molecular evolution in primates.Semantic proximity Read ↗

Alterations to the remote control of Shh gene expression cause congenital abnormalities.Semantic proximity Read ↗

The Hedgehog Signal Transduction NetworkSemantic proximity Read ↗

Enhancer adoption caused by genomic insertion elicits interdigital Shh expression and syndactyly in mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.