Article
Candidate gene associations reveal sex-specific Graves' disease risk alleles among Chinese Han populations.
Molecular genetics & genomic medicine - 1 Jul 2020
Yan Chen-Yan, Ma Yu-Ru, Sun Feng, Zhang Rui-Jia, Fang Ya, Zhang Qian-Yue, Wu Feng-Yao, Zhao Shuang-Xia, Song Huai-Dong
Abstract excerpt
BACKGROUND: With several susceptibility single nucleotide polymorphisms identified by case-control association studies, Graves' disease is one of the most common forms of autoimmune thyroid disease. In this study, we aimed to determine whether any observed differences in genetic associations are influenced by sex in Chinese Han populations. METHODS: A total of 8,835 patients with Graves' disease and 9,936...
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