Article
Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves' disease.
The Journal of clinical endocrinology and metabolism - 1 Feb 2015
Oryoji Daisuke, Ueda Sho, Yamamoto Ken, Yoshimura Noh Jaeduk, Okamura Ken, Noda Mitsuhiko, Watanabe Natsuko, Yoshihara Ai, Ito Koichi, Sasazuki Takehiko
Abstract excerpt
BACKGROUND: Hashimoto thyroiditis (HT) and Graves' disease (GD) share some immunological features. Determining the genetic basis that distinguishes HT from GD is key for a better understanding of the differences between these two related diseases. AIM: The aim of this study was to identify a non-HLA susceptibility locus that is specific to either HT or GD. DESIGN: We performed a two-stage genome-wide comparison...
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