Article
An X chromosome-wide association analysis identifies variants in GPR174 as a risk factor for Graves' disease.
Journal of medical genetics - 1 Jul 2013
Chu Xun, Shen Min, Xie Fang, Miao Xiao-Jing, Shou Wei-Hua, Liu Lin, Yang Peng-Peng, Bai Ya-Nan, Zhang Kai-Yue, Yang Lin, Hua Qi, Liu Wen-Dong, Dong Yan, Wang Hai-Feng, Shi Jin-Xiu, Wang Yi, Song Huai-Dong, Chen Sai-Juan, Chen Zhu, Huang Wei
Abstract excerpt
BACKGROUND: Graves' disease is a female preponderant autoimmune illness and the contribution of the X chromosome to its risk has long been appreciated. However, no X-linked susceptibility loci have been indentified from recent genome-wide association studies (GWAS). METHODS: We re-examined the X chromosome data from our recent GWAS for Graves' disease by including males that were previously excluded from the X...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.