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Article

Prediction of treatment outcomes for multidrug-resistant tuberculosis by whole-genome sequencing.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jul 2020

He Guiqing, Li Yang, Chen Xinchang, Chen Jiazhen, Zhang Wenhong

Abstract excerpt

BACKGROUND: Whole-genome sequencing (WGS) has been proposed to be a powerful tool to predict drug resistance for antitubercular drugs. However, the feasibility of WGS in predicting final treatment outcomes for multidrug-resistant tuberculosis (MDR-TB) patients remains unclear PATIENTS AND METHODS: In this prospective observational study conducted from January 2014 to September 2016, MDR-TB patients were enrolled...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32339719
DOI: 10.1016/j.ijid.2020.04.043

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