Article
Early-Onset Alzheimer's Disease: What Is Missing in Research?
Current neurology and neuroscience reports - 19 Jan 2021
Ayodele Temitope, Rogaeva Ekaterina, Kurup Jiji T, Beecham Gary, Reitz Christiane
Abstract excerpt
PURPOSE OF REVIEW: Early-onset Alzheimer's disease (EOAD), defined as Alzheimer's disease (AD) occurring before age 65, is significantly less well studied than the late-onset form (LOAD) despite EOAD often presenting with a more aggressive disease progression. The aim of this review is to summarize the current understanding of the etiology of EOAD, their translation into clinical practice, and to suggest steps to...
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