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Molecular biology and genetics of Alzheimer's disease

4 Jan 2005

Abstract excerpt

Like several other adult onset neurodegenerative diseases, Alzheimer's disease is a multifactorial illness with both genetic and non-genetic causes. Recent genetic studies have identified four genes associated with inherited risk for AD (presenilin 1, presenilin 2, amyloid precursor protein, and apolipoprotein E). These genes account for about half of the total genetic risk for Alzheimer's disease. It is...

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PMID: 15770998
DOI: 10.1016/j.crvi.2004.10.013

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