Article
Alzheimer's Disease: An Updated Overview of Its Genetics.
International journal of molecular sciences - 13 Feb 2023
Andrade-Guerrero Jesús, Santiago-Balmaseda Alberto, Jeronimo-Aguilar Paola, Vargas-Rodríguez Isaac, Cadena-Suárez Ana Ruth, Sánchez-Garibay Carlos, Pozo-Molina Glustein, Méndez-Catalá Claudia Fabiola, Cardenas-Aguayo Maria-Del-Carmen, Diaz-Cintra Sofía, Pacheco-Herrero Mar, Luna-Muñoz José, Soto-Rojas Luis O
Abstract excerpt
Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is classified as familial and sporadic. The dominant familial or autosomal presentation represents 1-5% of the total number of cases. It is categorized as early onset (EOAD; <65 years of age) and presents genetic mutations in presenilin 1 (PSEN1), presenilin 2 (PSEN2), or the Amyloid precursor protein (APP). Sporadic AD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.