Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of HLA-B*52:01-Driven Escape Mutations on Viral Replicative Capacity.

Journal of virology - 16 Jun 2020

Tsai Ming-Han Chloe, Singh Supriya, Adland Emily, Goulder Philip

Abstract excerpt

HLA-B*52:01 is strongly associated with protection against HIV disease progression. However, the mechanisms of HLA-B*52:01-mediated immune control have not been well studied. We here describe a cohort with a majority of HIV C-clade-infected individuals from Delhi, India, where HLA-B*52:01 is highly prevalent (phenotypic frequency, 22.5%). Consistent with studies of other cohorts, expression of HLA-B*52:01 was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epitopes, T-Lymphocyte
Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, MHC Class I

Share to HIV Core Protein p24

Share to Immune Evasion

Share to Immunodominant Epitopes

Share to T-Lymphocytes, Cytotoxic

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 32321820
DOI: 10.1128/JVI.02025-19
PMCID: PMC7307159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of HLA-B*52:01-Driven Escape Mutations on Viral Replicative Capacity.PMID 32321820Read ↗

HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703.Semantic proximity Read ↗

Genetic correlates influencing immunopathogenesis of HIV infection.Semantic proximity Read ↗

HIV subtype influences HLA-B*07:02-associated HIV disease outcome.Semantic proximity Read ↗

Virological and immunological factors associated with HIV-1 differential disease progression in HLA-B 58:01-positive individuals.Semantic proximity Read ↗

Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints.Semantic proximity Read ↗

Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.Semantic proximity Read ↗

Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control.Semantic proximity Read ↗

Multilayered defense in HLA-B51-associated HIV viral control.Semantic proximity Read ↗

Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection.Semantic proximity Read ↗

HLA Class I-Driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: Immune Escape and Viral LoadSemantic proximity Read ↗

HIV-1 evades a Gag mutation that abrogates killer cell immunoglobulin-like receptor binding and disinhibits natural killer cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype.Semantic proximity Read ↗

Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.