Article
Complete characterization of the human immune cell transcriptome using accurate full-length cDNA sequencing.
Genome research - 1 Apr 2020
Cole Charles, Byrne Ashley, Adams Matthew, Volden Roger, Vollmers Christopher
Abstract excerpt
The human immune system relies on highly complex and diverse transcripts and the proteins they encode. These include transcripts encoding human leukocyte antigen (HLA) receptors as well as B cell and T cell receptors (BCR and TCR). Determining which alleles an individual possesses for each HLA gene (high-resolution HLA typing) is essential to establish donor-recipient compatibility in organ and bone marrow...
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