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Article

Common variants in ABCA7 and MS4A6A are associated with cortical and hippocampal atrophy.

Neurobiology of aging - 1 Mar 2016

Ramirez Leslie M, Goukasian Naira, Porat Shai, Hwang Kristy S, Eastman Jennifer A, Hurtz Sona, Wang Benjamin, Vang Nouchee, Sears Renee, Klein Eric, Coppola Giovanni, Apostolova Liana G

Abstract excerpt

The precise physiologic function of many of the recently discovered Alzheimer's disease risk variants remains unknown. The downstream effects of genetic variants remain largely unexplored. We studied the relationship between the top 10 non-APOE genes with cortical and hippocampal atrophy as markers of neurodegeneration using 1.5T magnetic resonance imaging, 1-million single nucleotide polymorphism Illumina Human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26923404
DOI: 10.1016/j.neurobiolaging.2015.10.037

Genes

ABCA7
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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