Article

Sex-Specific causal dynamic between Insulin resistance and MDD, a bidirectional Mendelian randomization study

2024-07-16

Abstract excerpt

<h4>Aims/hypothesis</h4> Observational studies have shown a bidirectional association between major depressive disorder (MDD), Insulin resistance (IR), and related diseases, which varies between sexes and ancestries. We conducted a sex-specific two-sample bidirectional Mendelian randomization (MR) study to assess the causal associations of MDD with Insulin resistance measured through the TG: HDL-C ratio and vice v...

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Literature Corpus work: f8a3b91d-00a4-5bb2-9005-321be08abf3b
DOI: 10.1101/2024.07.16.24310339

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