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Article

A dominant-negative ESCRT-III protein perturbs cytokinesis and trafficking to lysosomes.

The Biochemical journal - 15 Apr 2008

Dukes Joseph D, Richardson Judith D, Simmons Ruth, Whitley Paul

Abstract excerpt

In eukaryotic cells, the completion of cytokinesis is dependent on membrane trafficking events to deliver membrane to the site of abscission. Golgi and recycling endosomal-derived proteins are required for the terminal stages of cytokinesis. Recently, protein subunits of the ESCRT (endosomal sorting complexes required for transport) that are normally involved in late endosome to lysosome trafficking have also...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18076377
DOI: 10.1042/BJ20071296

Genes

CHMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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