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Article

Transduction and Expansion of Primary T Cells in Nine Days with Maintenance of Central Memory Phenotype.

Journal of visualized experiments : JoVE - 18 Mar 2020

Pampusch Mary S, Skinner Pamela J

Abstract excerpt

Emerging immunotherapies to treat infectious diseases and cancers often involve transduction of cellular populations with genes encoding disease-targeting proteins. For example, chimeric antigen receptor (CAR)-T cells to treat cancers and viral infections involve the transduction of T cells with synthetic genes encoding CAR molecules. The CAR molecules make the T cells specifically recognize and kill cancer or...

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Share to Cell Culture Techniques
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Receptors, Antigen, T-Cell

Share to Receptors, Chimeric Antigen

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Source

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Identifiers

PMID: 32250358
DOI: 10.3791/60400
PMCID: PMC9411022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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