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Article

Penalized partial least squares for pleiotropy.

BMC bioinformatics - 24 Feb 2021

Broc Camilo, Truong Therese, Liquet Benoit

Abstract excerpt

BACKGROUND: The increasing number of genome-wide association studies (GWAS) has revealed several loci that are associated to multiple distinct phenotypes, suggesting the existence of pleiotropic effects. Highlighting these cross-phenotype genetic associations could help to identify and understand common biological mechanisms underlying some diseases. Common approaches test the association between genetic variants...

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PMID: 33627076
DOI: 10.1186/s12859-021-03968-1
PMCID: PMC7905667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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