Article
Resampling-based tests for Lasso in genome-wide association studies.
BMC genetics - 24 Jul 2017
Arbet Jaron, McGue Matt, Chatterjee Snigdhansu, Basu Saonli
Abstract excerpt
BACKGROUND: Genome-wide association studies involve detecting association between millions of genetic variants and a trait, which typically use univariate regression to test association between each single variant and the phenotype. Alternatively, Lasso penalized regression allows one to jointly model the relationship between all genetic variants and the phenotype. However, it is unclear how to best conduct...
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