Article
HLA-G 14 bp In/Del and +3142 C/G genotypes are differentially expressed between patients with grade IV gliomas and controls.
The International journal of neuroscience - 1 Apr 2021
de Magalhães Kênia Cristina S F, Silva Karla R, Gomes Nathália A, Sadissou Ibrahim, Carvalho Gérvasio T, Buzellin Marcelo A, Tafuri Luciene S, Nunes Cristiana B, Nunes Maurício B, Donadi Eduardo A, da Silva Istéfani Luciene, Simões Renata T
Abstract excerpt
Aim: Human Leukocyte Antigen-G (HLA-G) is a non-classical class I molecule that is involved in maternal-fetal immunotolerance. In cancer, this molecule contributes to the tumor escape. The aim of this study was to evaluate the 14 bp In/Del and +3142 C > G polymorphisms of the HLA-G 3' UTR and its relation with plasma and tissue HLA-G expression in patients with grade IV (high-grade) and grade I/II (low-grade)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.