Article
HLA-G polymorphisms, genetic susceptibility, and clinical outcome in childhood neuroblastoma.
Tissue antigens - 1 Dec 2011
Lau D T, Norris M D, Marshall G M, Haber M, Ashton L J
Abstract excerpt
Neuroblastoma is the most common solid tumor in children less than 5 years of age. The early onset of neuroblastoma suggests that genes involved in fetal development and pregnancy may have a putative role in the etiology of neuroblastoma. The human leukocyte antigen subtype G (HLA-G) molecule plays an important role in immune response regulation and appears to regulate immune tolerance during early pregnancy as...
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