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Heterogeneity of HLA-G Expression in Cancers: Facing the Challenges

27 Sept 2018

Abstract excerpt

Phenotypic heterogeneity has been observed in most malignancies, which represents a considerable challenge for tumor therapy. In recent decades, the biological function and clinical significance of the human leukocyte antigen (HLA)-G have been intensively explored. It is now widely accepted that HLA-G is a critical marker of immunotolerance in cancer cell immune evasion and is strongly associated with disease...

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PMID: 30319626
DOI: 10.3389/fimmu.2018.02164

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