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Article

Implication of Soluble HLA-G and HLA-G +3142G/C Polymorphism in Breast Cancer Patients Receiving Adjuvant Therapy in Tanzania.

Asian Pacific journal of cancer prevention : APJCP - 1 Nov 2019

Adolf Ismael Chatita, Akan Gokce, Mselle Teddy F, Dharsee Nazima, Namkinga Lucy A, Atalar Fatmahan

Abstract excerpt

BACKGROUND: During cancer growth, immunosuppressive microenvironment is created that enables tumour cells to evade an eliminative immune response and hence manage to grow into malignancy. HLA-G, existing as either membrane-bound (mHLA-G) or soluble (sHLA-G) molecule is thought to be immunosuppressive and produced more by tumor cells. The +3142G/C polymorphism in HLA-G gene affects its expression, and G allele is...

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Source

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Identifiers

PMID: 31759373
DOI: 10.31557/APJCP.2019.20.11.3465
PMCID: PMC7062990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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