Article

Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

2024-10-07

Abstract excerpt

<h4>ABSTRACT</h4> In animals, mitosis involves the breakdown of the nucleus. The reassembly of a nucleus after mitosis requires the reformation of the nuclear envelope around a single mass of chromosomes. This process requires Ankle2 (also known as LEM4 in humans) which interacts with PP2A and promotes the function of Barrier-to-Autointegration Factor (BAF). Upon dephosphorylation, BAF dimers cross-bridge chromos...

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Literature Corpus work: c84b79dd-2f0e-5ebd-a77d-0aba8cef32c0
DOI: 10.1101/2024.10.07.617051

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