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Histone Modifications in Alzheimer’s Disease

29 Jan 2023

Abstract excerpt

Since Late-onset Alzheimer's disease (LOAD) derives from a combination of genetic variants and environmental factors, epigenetic modifications have been predicted to play a role in the etiopathology of LOAD. Along with DNA methylation, histone modifications have been proposed as the main epigenetic modifications that contribute to the pathologic mechanisms of LOAD; however, little is known about how these...

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PMID: 36833274
DOI: 10.3390/genes14020347

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