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Article

A parallelized strategy for epistasis analysis based on Empirical Bayesian Elastic Net models.

Bioinformatics (Oxford, England) - 1 Jun 2020

Wen Jia, Ford Colby T, Janies Daniel, Shi Xinghua

Abstract excerpt

MOTIVATION: Epistasis reflects the distortion on a particular trait or phenotype resulting from the combinatorial effect of two or more genes or genetic variants. Epistasis is an important genetic foundation underlying quantitative traits in many organisms as well as in complex human diseases. However, there are two major barriers in identifying epistasis using large genomic datasets. One is that epistasis...

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PMID: 32227194
DOI: 10.1093/bioinformatics/btaa216
PMCID: PMC7320619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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