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Article

MatrixEpistasis: ultrafast, exhaustive epistasis scan for quantitative traits with covariate adjustment.

Bioinformatics (Oxford, England) - 15 Jul 2018

Zhu Shijia, Fang Gang

Abstract excerpt

Motivation: For many traits, causal loci uncovered by genetic mapping studies explain only a minority of the heritable contribution to trait variation. Multiple explanations for this 'missing heritability' have been proposed. Single nucleotide polymorphism (SNP)-SNP interaction (epistasis), as one of the compelling models, has been widely studied. However, the genome-wide scan of epistasis, especially for...

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Identifiers

PMID: 29509873
DOI: 10.1093/bioinformatics/bty094
PMCID: PMC6041989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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