Article
PRDM15 Is Associated with Risk of Chronic Obstructive Pulmonary Disease in a Rural Population in Chile.
Respiration; international review of thoracic diseases - 1 Jan 2000
Hosgood Iii H Dean, Díaz-Peña Roberto, Blansky Deanna, Jaime Sergio, Parra Viviana, Boekstegers Felix, Bermejo Justo Lorenzo, García-Valero José, Montes Juan F, Valdivia Gonzalo, Miravitlles Marc, Agustí Àlvar, Silva Rafael S, Olloquequi Jordi
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have accelerated our understanding of the genetic underpinnings of chronic obstructive pulmonary disease (COPD); however, GWAS populations have typically consisted of European descent, with ∼1% of Latin American ancestry. OBJECTIVE: To overcome this limitation, we conducted a GWAS in a rural Chilean population with increased COPD risk to investigate genetic...
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