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Immunostaining of scrapie cerebral amyloid plaques with antisera raised to scrapie-associated fibrils (SAF).

Neuropathology and applied neurobiology - 1 Jan 2000

McBride P A, Bruce M E, Fraser H

Abstract excerpt

Brain sections from 16 different mouse scrapie models were immunostained with antisera to scrapie-associated fibrils (SAF) from three experimental scrapie sources (hamster 263K, mouse ME7 and mouse 22L). These models involved seven strains of scrapie injected intracerebrally or intraperitoneally into a range of inbred mouse strains, producing a wide variety of neuropathological changes. The only brain structures...

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PMID: 3221978
DOI: 10.1111/j.1365-2990.1988.tb00892.x

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