Article
Retinopathy in mice with experimental scrapie.
Neuropathology and applied neurobiology - 1 Jan 2000
Foster J D, Fraser H, Bruce M E
Abstract excerpt
Scrapie is a naturally occurring neurological disease of adult sheep and goats with an incubation period of several years. Some strains of the causal agent can infect laboratory mice in which the incubation period, as well as the severity and distribution of vacuolar degeneration in the brain, varies according to the strain of the agent and the genotype of the mouse. Retinopathy, involving the partial or complete...
Topics
- Animals
- Brain
- Female
- Genotype
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Retina
- Scrapie
- Species Specificity
- Vacuoles
