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Article

Regulation of body length and bone mass by Gpr126/Adgrg6.

Science advances - 1 Mar 2020

Sun Peng, He Liang, Jia Kunhang, Yue Zhiying, Li Shichang, Jin Yunyun, Li Zhenxi, Siwko Stefan, Xue Feng, Su Jiacan, Liu Mingyao, Luo Jian

Abstract excerpt

Adhesion G protein-coupled receptor G6 (Adgrg6; also named GPR126) single-nucleotide polymorphisms are associated with human height in multiple populations. However, whether and how GPR126 regulates body height is unknown. In this study, we found that mouse body length was specifically decreased in Osx-Cre;Gpr126fl/fl mice. Deletion of Gpr126 in osteoblasts resulted in a remarkable delay in osteoblast...

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Share to Body Height
Share to Bone and Bones
Share to Calcification, Physiologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen Type IV

Share to Organ Size

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Share to Receptors, G-Protein-Coupled

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Source

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Identifiers

PMID: 32219165
DOI: 10.1126/sciadv.aaz0368
PMCID: PMC7083604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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