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Article

The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse.

PloS one - 18 Nov 2010

Waller-Evans Helen, Prömel Simone, Langenhan Tobias, Dixon John, Zahn Dirk, Colledge William H, Doran Joanne, Carlton Mark B L, Davies Ben, Aparicio Samuel A J R, Grosse Johannes, Russ Andreas P

Abstract excerpt

Adhesion-GPCRs provide essential cell-cell and cell-matrix interactions in development, and have been implicated in inherited human diseases like Usher Syndrome and bilateral frontoparietal polymicrogyria. They are the second largest subfamily of seven-transmembrane spanning proteins in vertebrates, but the function of most of these receptors is still not understood. The orphan Adhesion-GPCR GPR126 has recently...

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Share to Cardiovascular Abnormalities
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Developmental

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Share to Myocardium

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Share to Receptors, G-Protein-Coupled

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Identifiers

PMID: 21124978
DOI: 10.1371/journal.pone.0014047
PMCID: PMC2987804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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