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Article

Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries.

PloS one - 1 Jan 2014

Tan Li-Jun, Zhu Hu, He Hao, Wu Ke-Hao, Li Jian, Chen Xiang-Ding, Zhang Ji-Gang, Shen Hui, Tian Qing, Krousel-Wood Marie, Papasian Christopher J, Bouchard Claude, Pérusse Louis, Deng Hong-Wen

Abstract excerpt

Obesity is a major public health problem with a significant genetic component. Multiple DNA polymorphisms/genes have been shown to be strongly associated with obesity, typically in populations of European descent. The aim of this study was to verify the extent to which 6 confirmed obesity genes (FTO, CTNNBL1, ADRB2, LEPR, PPARG and UCP2 genes) could be replicated in 8 different samples (n = 11,161) and to explore...

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Identifiers

PMID: 24879436
DOI: 10.1371/journal.pone.0096149
PMCID: PMC4039436

Genes

FTO
CTNNBL1
LEPR
PPARG
ADRB2
UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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