Article
The genetics of obesity: FTO leads the way.
Trends in genetics : TIG - 1 Jun 2010
Fawcett Katherine A, Barroso Inês
Abstract excerpt
In 2007, an association of single nucleotide polymorphisms (SNPs) in the fat mass and obesity-associated (FTO) gene region with body mass index (BMI) and risk of obesity was identified in multiple populations, making FTO the first locus unequivocally associated with adiposity. At the time, FTO was a gene of unknown function and it was not known whether these SNPs exerted their effect on adiposity by affecting FTO...
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