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Article

The association between sarcopenia susceptibility and polymorphisms of FTO, ACVR2B, and IRS1 in Tibetans.

Molecular genetics & genomic medicine - 1 Aug 2021

Zhang Xianpeng, Ye Liping, Li Xin, Chen Ying, Jiang Yaqiong, Li Wenhui, Wen Youfeng

Abstract excerpt

BACKGROUND: Hypoxia within the plateau has a negative effect on skeletal muscle and may play a role in the development of sarcopenia in humans. Tibetans having lived in the Qinghai-Tibet Plateau for thousands of years, are a high-risk group for sarcopenia; however, they have a distinctive suite of genetic traits that enable them to tolerate environmental hypoxia and are genetically significantly different from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

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Source

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Identifiers

PMID: 34302448
DOI: 10.1002/mgg3.1747
PMCID: PMC8404241

Genes

FTO
ACVR2B
IRS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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