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Killer cell immunoglobulin-like receptors (KIR) and human leukocyte antigen-C (HLA-C) allorecognition patterns in women with endometriosis.

Scientific reports - 17 Mar 2020

Chou Ya-Ching, Chen Chi-Huang, Chen Ming-Jer, Chang Ching-Wen, Chen Pi-Hua, Yu Mu-Hsien, Chen Yi-Jen, Tsai Eing-Mei, Yang Peng-Sheng, Lin Shyr-Yeu, Tzeng Chii-Ruey

Abstract excerpt

Endometriosis shares similarities with several autoimmune diseases. The human leukocyte antigen (HLA)-C genotype is associated with several human autoimmune diseases. HLA-C is a ligand of killer cell immunoglobulin receptors (KIRs) and is an essential regulator of natural killer cell activity, which is associated with endometriosis progression. Polymorphisms in HLA-C and KIR affect the activity of NK cells and...

Topics

Adult
Endometriosis
Female
Genetic Predisposition to Disease
Genotype
HLA-C Antigens
Humans
Middle Aged
Receptors, KIR

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32184413
DOI: 10.1038/s41598-020-61702-y
PMCID: PMC7078270

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Killer cell immunoglobulin-like receptors (KIR) and human leukocyte antigen-C (HLA-C) allorecognition patterns in women with endometriosis.PMID 32184413Read ↗

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