Article
Inhibitory KIR2DL2 Gene: Risk for Deep Endometriosis in Euro-descendants.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Jan 2021
Marin Maria Lucia Carnevale, Coelho Verônica, Visentainer Jeane Eliete Laguila, Alves Hugo Vicentin, Köhler Karen Francine, Rached Marici Rached, Abrão Mauricio Simões, Kalil Jorge
Abstract excerpt
Endometriosis (EDT) is an inflammatory disease characterized by implantation/growth of endometrial tissue, glands, and/or stroma, outside the uterus. Reduced NK cell cytotoxic activity has been implicated in its pathogenesis, together with other immunologic alterations. We investigated the influence of KIR gene polymorphisms and their HLA ligand combinations in deep endometriosis (DE) susceptibility. One hundred...
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