Article
KIR2DS5 in the presence of HLA-C C2 protects against endometriosis.
Immunogenetics - 1 Apr 2015
Nowak Izabela, Płoski Rafał, Barcz Ewa, Dziunycz Piotr, Kamiński Paweł, Kostrzewa Grażyna, Milewski Łukasz, Roszkowski Piotr I, Senitzer David, Malejczyk Jacek, Kuśnierczyk Piotr
Abstract excerpt
Endometriosis is defined as the presence of functional endometrial tissue outside the uterine cavity. Several hypotheses have attempted to explain the etiology and pathogenesis of endometriosis. Recently, it has been suggested that a defect of the natural killer (NK) activity in the recognition and lysis of endometrial cells is one of the crucial points in the development of this disease. Natural killer cells can...
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