Article
Association of killer cell immunoglobulin-like receptor genotypes with susceptibility to endometriosis.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Dec 2007
Kitawaki Jo, Xu Bing, Ishihara Hiroaki, Fukui Michiaki, Hasegawa Goji, Nakamura Naoto, Mizuno Shigeto, Ohta Mitsuhiro, Obayashi Hiroshi, Honjo Hideo
Abstract excerpt
PROBLEM: Endometriosis is an immune-related chronic inflammatory disease with a polygenic predisposition. The aim of this study was to investigate whether polymorphisms in killer cell immunoglobulin-like receptors (KIRs) is responsible, in part, for genetic susceptibility to endometriosis. METHOD OF STUDY: The KIRs genotype was determined in 186 patients with endometriosis and 165 control women using polymerase...
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