Article
Decreased HLA-C1 alleles in couples of KIR2DL2 positive women with recurrent pregnancy loss.
Journal of reproductive immunology - 1 Nov 2020
Yang Xiuhua, Yang Ellen, Wang Wen-Juan, He Qiaohua, Jubiz Giovanni, Katukurundage Dimantha, Dambaeva Svetlana, Beaman Kenneth, Kwak-Kim Joanne
Abstract excerpt
Specific killer cell immunoglobulin-like receptor (KIR) in women with recurrent pregnancy loss (RPL) and HLA ligands in couples invoke a susceptibility to RPL. However, the relationship between KIR2DL2 and its cognate ligand HLA-C1 has not been explored. In this prospective cohort study, 160 Caucasian women with RPL and 99 partners were included. KIR/HLA-C typing, NK assay, Th1/Th2 intracellular cytokine ratios,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
