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Article

Clinical implications of APOBEC3A and 3B expression in patients with breast cancer.

PloS one - 1 Jan 2020

Kim Yong-Seok, Sun Der Sheng, Yoon Jung-Sook, Ko Yoon Ho, Won Hye Sung, Kim Jeong Soo

Abstract excerpt

BACKGROUND: We aimed to evaluate the expression of APOBEC3A (A3A), 3B (A3B) mRNA, and germline APOBEC3A/B deletion polymorphism in patients with breast cancers and to investigate the correlation between their expressions and clinicopathological characteristics. METHODS: RNA and DNA samples were extracted from 138 breast cancer tissues and adjacent normal breast tissues. The levels of A3A and A3B mRNA transcripts...

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Identifiers

PMID: 32176735
DOI: 10.1371/journal.pone.0230261
PMCID: PMC7075570

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Clinical implications of APOBEC3A and 3B expression in patients with breast cancer.PMID 32176735Read ↗

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