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Article

Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.

PloS one - 1 Jan 2016

Tokunaga Eriko, Yamashita Nami, Tanaka Kimihiro, Inoue Yuka, Akiyoshi Sayuri, Saeki Hiroshi, Oki Eiji, Kitao Hiroyuki, Maehara Yoshihiko

Abstract excerpt

Recent studies have identified the apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3B (APOBEC3B) as a source of mutations in various malignancies. APOBEC3B is overexpressed in several human cancer types, including breast cancer. In this study, we analyzed APOBEC3B mRNA expression in 305 primary breast cancers of Japanese women using quantitative reverse transcription-PCR, and investigated the...

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Identifiers

PMID: 27977754
DOI: 10.1371/journal.pone.0168090
PMCID: PMC5158016

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