Article
Pri-miR-34b/c rs4938723 TC heterozygote is associated with increased cancer risks: evidence from published data.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2014
Yi De-Hui, Wang Ben-Gang, Zhong Xin-Ping, Liu Hao, Liu Yong-Feng
Abstract excerpt
The promoter region of the microRNA pri-miR-34b/c has a potentially functional polymorphism, rs4938723, located in a typical CpG island. Studies of the association between pri-miR-34b/c rs4938723 polymorphism and risks of various cancers have had inconsistent results. We therefore conducted a meta-analysis of nine studies that included 6,036 cancer patients and 7,490 controls to address this association. Overall,...
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