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Article

Promoter polymorphisms of pri-miR-34b/c are associated with hepatocellular carcinoma.

Gene - 25 Jul 2013

Son Myung Su, Jang Moon Ju, Jeon Young Joo, Kim Won Hee, Kwon Chang-Il, Ko Kwang Hyun, Park Pil Won, Hong Sung Pyo, Rim Kyu Sung, Kwon Sung Won, Hwang Seong Gyu, Kim Nam Keun

Abstract excerpt

BACKGROUND: Numerous studies have focused on the association between miR-34 family members, which are direct p53 targets, and carcinogenesis of many cancers, including hepatocellular carcinoma (HCC). This study aimed to assess whether polymorphisms in the single-nucleotide polymorphism miR-34b/c T>C (rs4938723) and TP53 Arg72Pro (rs1042522) increase the risk of HCC and influence outcome in patients with HCC....

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Identifiers

PMID: 23632240
DOI: 10.1016/j.gene.2013.04.042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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