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Article

Evolution at protein ends: major contribution of alternative transcription initiation and termination to the transcriptome and proteome diversity in mammals.

Nucleic acids research - 1 Jun 2014

Shabalina Svetlana A, Ogurtsov Aleksey Y, Spiridonov Nikolay A, Koonin Eugene V

Abstract excerpt

Alternative splicing (AS), alternative transcription initiation (ATI) and alternative transcription termination (ATT) create the extraordinary complexity of transcriptomes and make key contributions to the structural and functional diversity of mammalian proteomes. Analysis of mammalian genomic a...

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PMID: 24792168
DOI: 10.1093/nar/gku342
PMCID: PMC4066770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24792168-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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