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Article

The Impact of KRAS Mutation on the Presentation and Prognosis of Non-Metastatic Colon Cancer: an Analysis from the National Cancer Database.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Jun 2020

Scott Aaron, Goffredo Paolo, Ginader Timothy, Hrabe Jennifer, Gribovskaja-Rupp Irena, Kapadia Muneera R, Weigel Ronald J, Hassan Imran

Abstract excerpt

INTRODUCTION: Approximately 40% of colorectal cancers have a KRAS mutation. The prognostic significance of KRAS mutations in patients with non-metastatic colon cancer has not been well elucidated. The National Cancer Database (NCDB) was used to analyze factors associated with KRAS mutation as well as its impact on the presentation and survival of patients with stages I-III colon cancer. METHODS: The NCDB was...

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Identifiers

PMID: 32128676
DOI: 10.1007/s11605-020-04543-4

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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