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Article

Collective effects of long-range DNA methylations predict gene expressions and estimate phenotypes in cancer.

Scientific reports - 3 Mar 2020

Kim Soyeon, Park Hyun Jung, Cui Xiangqin, Zhi Degui

Abstract excerpt

DNA methylation of various genomic regions has been found to be associated with gene expression in diverse biological contexts. However, most genome-wide studies have focused on the effect of (1) methylation in cis, not in trans and (2) a single CpG, not the collective effects of multiple CpGs, on gene expression. In this study, we developed a statistical machine learning model, geneEXPLORE (gene expression...

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Identifiers

PMID: 32127627
DOI: 10.1038/s41598-020-60845-2
PMCID: PMC7054398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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