Article

Integration of public DNA methylation and expression networks via eQTMs improves prediction of functional gene–gene associations

2021-12-18

Abstract excerpt

Gene co-expression networks can be used to infer functional relationships between genes, but they do not work well for all genes. We investigated whether DNA methylation can provide complementary information for such genes. We first carried out an eQTM meta-analysis of 3,574 gene expression and methylation samples from blood, brain and nasal epithelial brushed cells to identify links between methylated CpG sites a...

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Literature Corpus work: fa2f5ea9-1163-5524-bcc7-3229f16abde5
DOI: 10.1101/2021.12.17.473125

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