Article
Circulating HIV-1 Integrase Genotypes in Tanzania: Implication on the Introduction of Integrase Inhibitors-Based Antiretroviral Therapy Regimen.
AIDS research and human retroviruses - 1 Jun 2020
Masoud Salim, Kamori Doreen, Barabona Godfrey, Mahiti Macdonald, Sunguya Bruno, Lyamuya Eligius, Ueno Takamasa
Abstract excerpt
Tanzania has recently adapted World Health Organization antiretroviral guidelines that include integrase strand transfer inhibitors (INSTIs) in the first-line regimen. However, there is lack of evidence on integrase (IN) gene polymorphisms in viral strains circulating in Tanzania. In this study, we characterize IN gene polymorphisms in viral strains circulating in Dar es Salaam, Tanzania, before introduction of...
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