Article
Resistance-Associated Mutations and Polymorphisms among Integrase Inhibitor-Naïve HIV-1 Patients in Kuwait.
Intervirology - 1 Jan 2017
Chehadeh Wassim, Albaksami Osama, John Sonia Elezebeth, Al-Nakib Widad
Abstract excerpt
OBJECTIVES: Resistance-associated mutations (RAMs) in the integrase of different HIV-1 subtypes were investigated in a cohort of patients never exposed to integrase strand transfer inhibitors (INSTIs). METHODS: The viral RNA was extracted from plasma samples of 53 INSTI-naïve patients, and the integrase genetic region was sequenced and analyzed for subtype assignment and drug resistance. RESULTS: The median viral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
